Dysregulation of the Golgi apparatus has emerged as a significant factor driving the
initiation and progression of cancer. My primary objective is to unravel the mechanisms
through which oncogenic somatic mutations impact the structure and secretory functions
of the Golgi organelle. This research will ultimately contribute to the development of
innovative therapeutic approaches based on a deeper understanding of these processes.
In addition to Golgi-related investigations, I am actively exploring the roles of endocytic
recycling pathways in human cancer. Our ongoing projects encompass two key areas: 1)
Investigating the functional roles of amplified Golgi genes in cancer initiation and
progression and 2) Identifying potential therapeutic Golgi target and developing novel
strategies for cancer treatment.
